SICLOPPS cyclic peptide libraries in drug discovery
نویسندگان
چکیده
منابع مشابه
Drug Discovery with Novel Chemical Libraries
Several drug discovery and design endevours are focused on an exhaustive exploration of the drug-like chemical space with the final goal of identifying compounds that can be developed clinically. The traditional drug-like chemical space has been defined using old drugs with empirical rules such as the Lipinski’s Rule-of-Five (RO5). Therefore, promising drug candidates may be overlooked because ...
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ژورنال
عنوان ژورنال: Current Opinion in Chemical Biology
سال: 2017
ISSN: 1367-5931
DOI: 10.1016/j.cbpa.2017.02.016